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This is a sendout test. Please note that turnaround time is defined as the anticipated time from set up day to results release.
S52525: Alpha-globin Gene Del/dup [16124x] Print View
Result      

PRIMARY
1 Whole Blood EDTA 5 (3) mL   Refrigerated - 8 Day(s)/Room Temperature - 8 Day(s)  
ALTERNATE
  Whole Blood Heparin 5 (3) mL   Refrigerated - 8 Day(s)/Room Temperature - 8 Day(s)  

This test ca be used to detect the presence of absence of large deletions in the HBA1 or HBA2 gene in patients or their family members suspected of having alpha thalassemia or who are carriers of alpha globin deletions. The assay can also be used in the prenatal diagnosis of alpha thalassemia. The assay does not determine the type or breakpoint of the rearrangement. This assay can be used instead of Southern Blot analysis to determine the total number of intact alpha globin genes.

Whole blood: Normal phlebotomy procedure. Specimen stability is
crucial. Store and ship at room temperature immediately. Do not
freeze. Amniotic fluid: Normal collection procedure. Specimen
stability is crucial. Store and ship at room temperature immediately.
Do not refrigerate or freeze. Amniocyte culture: Sterile T25
flask, filled with culture medium. Specimen stability is
crucial. Store and ship at room temperature immediately. Do not
regfrigerate or freeze. Dissected chorionic villi (CVS)
biopsy: 10-20 mg dissected CVS collected in sterile tube filled with
sterile culture medium. Specimen stability is crucial Store and ship
at room temperature immediately. Do not refrigerate or freeze.
Provide Family History; For prenatal diagnosis with a fetal specimen:
1) parents must be docummented carriers of on of the mutations
tested; 2)maternal blood or DNA must be available; 3) contact the
laboratory genetic counselor before submission. Provide Clinical
Information (MCV, Blood Work, Age, Alpha Globin mutations detected,
ethnicity). For other sample types please contact the laboratory.
Setup Schedule
Tuesday

Reported (Analytical Time)
21-23 days

CPT Code
81269

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes
Methodology: Multiplex PCR, Capillary Electrophoresis

This test is not approved for the testing of patient samples from New York state.

CPT CODES: 83891,83900,83909,83912,83901X12






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