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Allergy & Immunology

Cardiology & Coagulation

1726: Rapidly Progressive Glomerulonephritis Evaluation

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Glomerular Basement Membrane Autoantibodies	EIA	< 21	Units
ANCA Total Autoantibodies	IFA/IMAGE	< 1:20	FIU
ANCA Pattern	IFA	By Report
Myeloperoxidase Autoantibodies	EIA	< 9.0	U/mL
Proteinase-3 Autoantibodies	EIA	< 3.5	U/mL
Antinuclear Antibodies (ANA)	IFA/IMAGE	<7.5	IU/mL
ANA Pattern	IFA	By Report
C3 Complement	IMMUNOTURB	90 - 180	mg/dL
C4 Complement	IMMUNOTURB	16 - 47	mg/dL
Antistreptolysin O	TURB	< 18 years: < 150 >= 18 years: < 201	IU/mL


PRIMARY
1	Serum	3 (2) mL	Frozen - 28 Day(s)/Refrigerated - 7 Day(s)/Ambient - 48 Hour(s)

The classical cytoplasmic (C-ANCA) pattern of autoantibodies is associated with Wegener granulomatosis (WG). PR-3 autoantibodies generally confirm active WG. Perinuclear (P-ANCA) autoantibodies are rarely detected in WG. Detection of high concentrations of glomerular basement membrane autoantibodies (GBMA) strongly support the diagnosis of Goodpasture syndrome. Some patients with RPGN have both ANCA and GBMA.

Lipemic, and moderately or grossly icteric and hemolyzed samples
are not suitable for analysis.
Overnight fasting preferred. Serum should be separated immediately
from clot.

Setup Schedule

Friday

Reported (Analytical Time)

Same day

CPT Codes

83520, 86021x3, 86039, 86060, 86160x2

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Notes

Please refer to test code 1022 for ANCA isotyping (IgG, IgM, & IgA).

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