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#3131: Adenosine Deaminase COMPONENTS   Name Method Reference Range Units Adenosine Deaminase S U/L  SPECIMEN REQUIREMENTS   No Type Volume Temperature Container Type Instructions 1 - Primary Serum 1 (0.5) mL Frozen - 30 Day(s)/Ambient - 72 Hour(s)/Refrigerated - 30 Day(s) Aliquot   2 - Alternate Fluid Pleural 1 (0.5) mL Ambient - 72 Hour(s)/Frozen - 30 Day(s)/Refrigerated - 30 Day(s) Sterile   3 - Alternate CSF 1 (0.5) mL Frozen - 30 Day(s)/Ambient - 72 Hour(s)/Refrigerated - 30 Day(s) Sterile   GENERAL INFORMATION   Setup Schedule Wednesday, Friday Reported Same day CPT Code 84311 Notes Optimal results require testing within 1 month of collection. Prices might not include a handling fee. Test Performed At Specialty Laboratories, Inc. Clinical Utilities Adenosine deaminase (ADA) is an endogenous tissue enzyme which is released into the serum in patients with many different types of malignancies and infections, including viral hepatitis, infectious mononucleosis, typhoid fever, and tuberculosis. It is the most useful single test in portal hypertension (ascites) associated with liver cirrhosis. In pleural fluid, elevated ADA levels are very commonly associated with tuberculosis, although increased ADA activity may be found in effusions due to a number of causes, including TB, bacterial infections, rheumatologic disease, and lymphoproliferative disorders. In CSF, ADA is elevated in cases of tuberculous meningitis.   Collection Notes   Other acceptable specimens are: CSF and Pleural fluid. Collect in a screw-cap leak-proof tube.