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#CAFFE: CAFFEINE

COMPONENTS
Name Method Reference Range Units
Caffeine EMIT 5.5 - 16.2
Critical High: >=21.5
ug/mL

SPECIMEN REQUIREMENTS
No Type Volume Temperature Container Type Instructions
0 Serum 1 Refrigerate 7mL red top <2yrs: use pediatric SST (serum separator tube) Sample Collection Time:
Note: The patientís clinical condition and dosage regimen may influence the sample collection time.
1. Patient receiving Theophylline Intravenously:
a. Measure 30 minutes after completion of intravenous loading dose
b. Measure 4-6 hours after initiation of a constant rate infusion
c. Repeat measurement 12-18 hours after initiation of a constant rate infusion
d. Repeat measurement at 24-hours intervals unit infusion is discontinued

2. Patient receiving Theophylline Orally:
a. Measure trough concentration immediately before the next dose
b. Measure peak concentration according to the following:
c. Solution or uncoated tablet: 2 hours after oral dose
d. Slow-release formulations: 4 hours after oral dose

3. Patient receiving Caffeine Therapy:
a. Prior to dosing patients with caffeine, baseline serum levels of caffeine should be measured for:
1. infants born to mothers who consumed caffeine prior to delivery
2. infants previously dosed with theophylline
 

GENERAL INFORMATION
Setup Schedule Daily
Turn-Around Time 1 day
CPT Code 80299
Performing Lab GBMC
Test Performed Stat Yes