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Use & Interpretation of Laboratory Tests Books
Use & Interpretation of Laboratory Tests Books

Enterobius vermicularis
James B. Peter, M.D., Ph.D.

Enterobius vermicularis (pinworm), one of the most common helminthic infections,1  generally inhabits the large intestine but is of low pathogenicity. Occasionally, however, ova can be found in ectopic sites in the peritoneal cavity (often as asymptomatic granules) and sometimes in the appendix.2 Perianal itching in children is most often due to enterobiasis.3 Pelvic inflammatory disease can result from E. vermicularis infection.4

The cellophane tape procedure (CTP), which is the basis for diagnosis of enterobiasis (oxyuriasis) is improved by lacto-phenol cotton blue staining;5 the frequency of enterobiasis is thought to have decreased in the U.S.6 Three CTP exams detect 90% and five exams detect 99% of pinworm infections.7,8 A simple screening program is effective for elimination of pinworm from institutionalized patients.9 Testing for antibodies is not promising.10 Family status and personal hygiene are probably important in transmission of pinworm infection.11 Both normal and inflamed appendices can be infested.12 Ectopic enterobiasis is well recognized.13,14 A review on E. vermicularis symptoms, diagnosis and treatment is available.15


See Also:
Dipylidium caninum

REFERENCES

  1. Parija SC, Basile A, Nalini P. Enterobius vermicularis infection in children in Pondicherry. Biomedicine 1999;19:103-5.
  2. Listoro G, Ferranti F, Mancini G, et al. The role of Enterobius vermicularis in etiopathogenesis of appendicitis. Minvera Chir 1996;51:293-6.
  3. Van Zeijl JH, Korver CR. Perianal streptococcal dermatitis in children. Ned Tijdschr Geneeskd 1996;140:2191-3.
  4. Tandan T, Pollard AJ, Money DM, Scheifele DW. Pelvic inflammatory disease associated with Enterobius vermicularis. Arch Dis Child 2002;86:439-40.
  5. Parija SC, Sheeladevi C, Shivaprakash MR, Biswal N. Evaluation of lactophenol cotton blue stain for detection of eggs of Enterobius vermicularis in perianal surface samples. Trop Doct 2001;31:214-5.
  6. Vermund SH, MacLeod S. Is pinworm a vanishing infection? Laboratory surveillance in a New York City Medical Center from 1971 to 198 Am J Dis Child 1988;142:566-8.
  7. Sadun EH, Melvin DM. The probability of detecting infections with Enterobius vermicularis by successive examinations. J Pediatr 1956;48:438-41.
  8. Anonymous. Threadworms [Editorial]. Lancet 1946;1:742-3.
  9. Lohiya GS, Tan-Figueroa L, Crinella FM, Lohiya S. Epidemiology and control of enterobiasis in a developmental center. West J Med 2000;19:188-9.
  10. Fernandez M, Tabar A, Guisantes J, Oehling A. Incidence of intestinal parasitism in allergic children. Allergol Immunopathol (Madr) 1986;14:205-13.
  11. Chang JH, Huang WH, Chen ER, Hu SC. Survey of Enterobius vermicularis infection among school children in Tainan City. Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1990;6:587-93.
  12. Wiebe BM, Appendicitis and Enterobius vermicularis. Scand J Gastroenterol 1991;26:336-8.
  13. Tornieporth NG, Disko R, Brandis A, Bartuzki D. Ectopic enterobiasis: a case report and review. J Infect 1992;24:87-90.
  14. Sun T, Schwartz NS, Sewell C, Lieberman P, Gross S. Enterobius egg granuloma of the vulva and peritoneum: a review of the literature. Am J Trop Med Hyg 1991;45:249-53.
  15. Russell LJ. The pinworm, Enterobius vermicularis. Prim Care 1991;18:13-24.





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